121 Mining Investment – Hong Kong

THE CONFERENCE CALLER: Anybody interested in meeting with mining companies and resource-focused investors in October should be booking flights to Hong Kong right now.

Hong Kong, China’s international gateway city is to be the host city for the first natural resources event of the 121 Group.

The – 121 Mining Investment – conference, to be held in Hong Kong on 15-16 October 2014, promises delegates a time efficient opportunity for investors and miners to connect and strike deals.

 

The event will focus on showcasing quality mining investment opportunities from around the world, with the aim of matching sophisticated investors with high-potential mining projects.

“Seeing the lack of more effective and targeted forms of mining investment events in Asia, 121 Group’s objective is to fill this gap so that serious mining sector investors can have the ideal platform to meet with operators of quality mining projects from different parts of the world,” 121 Group managing partner Leo Stemp said.

“The two-day event will feature 1-2-1 set-ups for mining operators to showcase their projects, while interested investors will have the sufficient time to understand each investment opportunity thoroughly in a private and cozy setting.”

The conference promises to deliver more than the opportunity to discuss and review a diverse range of mining investment projects.

121 Mining Investment will also feature various industry-veteran keynote and panel speakers who will share insights on the latest topics in the natural resources field.

 Some of the confirmed topics include:

The investment opportunity of a lifetime?  Capitalising on the cyclical nature of the mining sector;

Global macro-economics and the impact on metals and minerals demand;

Investor Insights – What Asia’s investors are looking for in a mining investment;

China outbound trends – Why appetite from China for overseas mining deals is on the rise?

Private Equity in focus – The new force in mining finance?

Nickel, copper, bauxite and base metals: Commodities on the rise?

Coal – Demand, supply and role in the global energy mix;

Iron ore and ferro-alloys – Identifying winners and losers in a volatile market for steel raw materials;

Uranium equities outlook; and

Platinum group metals: Price and equities outlook with volatile drivers on both the supply and demand side.

To ensure top quality meetings and networking opportunities, entry to the event is strictly reserved for qualified investors, mining company management teams and selected investment-related service providers.

Registration is now open and more information regarding the event and registration procedures (including personalising schedules for 1-2-1 meetings during the two-day event) can be found here:

www.weare121.com/121mininginvestment-hk/


Founded by a team of experienced investment event professionals, 121 Group offers a range of tailored-investor-introduction and deal-sourcing-solutions for the natural resources sector.  With exclusive investment events and introduction services designed around the changing needs of the industry, 121 Group is dedicated to helping market participants meet their investment selection, capital raising and business development needs.  121 Group holds events in key financial centres including London, Cape Town and Hong Kong.  For more details, please visit
: www.weare121.com

Fund Raising across the Boards

THE FUND RAISER: Some renewed vigour provided a bit of spark to the Fund Raising front this week.

Completion of Share Placement

Echo Resources (ASX: EAR) has completed a placement of approx. 6.36 million fully paid ordinary shares at 11 cents per share to raise $700,040 before costs.

The shares have been placed to sophisticated and professional investors and rank equally with the company’s existing issued shares.

“We thank Echo’s new shareholders for their support,” Echo Resources managing director Dr Ernst Kohler said.

“Despite the difficult market conditions, we are very pleased that the capital raising was done at a 10 per cent premium to Echo’s closing share price on the previous trading day.”

The proceeds of the placement are intended to be used to advance Echo’s projects, including exploration drilling programs at the Julius gold discovery in central Western Australia, and for general working capital purposes.


Capital Raising

Promesa Limited (ASX: PRA) has undertaken a capital raising of $1 million via the issue of up to 40 million fully paid ordinary shares at 2.5 cents each.

The placement is being made to sophisticated and professional investors.

Proceeds from the placement will be used primarily to fund the company’s Stage 2 drilling program, the extension of the magnetic survey (two fold), upgrading of current permits increasing the area of influence four fold and allowing drilling beyond the current approved 20 platforms at the Alumbre copper-molybdenum porphyry project in Peru.


$3.7 Million R&D Tax Rebate

Carbon Energy (ASX: CNX) has received $3.7 million as a research and development (R&D) tax incentive cash rebate for R&D expenditure in the 2014 financial year.

The company has now repaid a $1.5 million Macquarie Bank loan facility in full.

Following the submission of its Decommissioning Report, Carbon Energy is continuing to prepare a Rehabilitation Plan for its BloodwoodCreek UCG trial site.

This is expected to be ready for lodgement with the Queensland Government by the end of September 2014.


Capital Raising

Wild Acre Metals (ASX: WAC) has received commitments to raise $300,000 by way of a placement of securities.

The placement will involve the issue of 20 million shares at an issue price of 1.5 cents per share together with one (1) unlisted option exercisable at 10 cents each within 3 years for every three (3) shares subscribed for under the placement.

Funds raised from the placement will be applied towards progressing the company’s Sambalay/Salvador high-grade silver project in Southern Peru, target generation at the Mt Ida gold/nickel project in Western Australia and for general working capital purposes.


MRL raises $1.1 million

MRL Corporation (ASX: MRF) is preparing to start a bulk sampling program at the company’s high-grade Warakapola graphite project in Sri Lanka.

The preparations follow the company raising $1.1 million through a share placement, which involved the placement of 16.4 million shares at 7 cents each to sophisticated investors from Asia.

The bulk sampling program, which is planned to commence in the December Quarter, is aimed at accelerating the start of commercial production of high-grade graphite at Warakapola following the award of an Industrial Mining Licence.

What the Analysts Say

WHAT THE ANALYSTS SAY: Interesting news and views from across the Resource Analyst universe.

Website: www.breakawayresearch.com

Company:  Kibaran Resources (ASX: KNL)

Kibaran is an ASX-listed graphite explorer and developer, concentrating efforts in Tanzania.

Its key project is the Epanko graphite deposit, within the broader Mahenge project area.

Having recently completed a Scoping Study, activities are now concentrated on moving to feasibility and then construction in early 2016.

The second project, Merelani-Arusha, is located adjacent to the previous producing Merelani graphite mine, which now concentrates on producing Tanzanite, a rare gem stone.

Kibaran are currently in negotiation with the owners of the mine, TanzaniteOne Mining Limited (TML) (a wholly-owned subsidiary of AIM-listed Richland Resources Limited) and Tanzania’s State Mining Corporation (‘STAMICO”) via their STAMICO-TML Joint Venture, with a view to combine the relevant companies’ assets by way of a JV and restarting graphite production.

The recently completed Scoping Study for the Epanko graphite deposit in southern Tanzania has, with an NPV of US$213 million, returned excellent results, indicating a long term, robust project with substantial upside through both resource and planned production expansion.

A key to the project is the likely quality of the graphite concentrate – testwork indicates the production of low contaminant, large flake graphite suitable for all applications, including the production of the value added expanded and spherical forms, which should command a premium price.

The quality is superior to that of most other ASX-listed graphite hopefuls.

The company will now move forward to a Feasibility Study, and is looking to fast track a relatively modest initial development with potential for expansion down the track.

The Merelani-Arusha project in Northern Tanzania is also a potential company-maker in its own right, with significant high grade graphite mineralisation close to a historically operating mine that could become a second producing asset for Kibaran.

Website: www.hartleys.com.au

Company: Predictive Discovery Ltd (ASX: PDI)

Maiden high grade resource at Bongou

Predictive Discovery recently announced a maiden JORC resource estimate for its Bongou gold deposit at the Bonsiega project in Burkina Faso.

The Bongou maiden resource estimate is 2.2 million tonnes (Mt) at 2.6 grams per tonne for 184,000 ounces (0.8g/t cutoff) with a high grade portion of 1.1Mt at 3.8g/t for 136,000 ounces (2g/t cutoff).

Bongou is a thick, steeply dipping gold mineralised granite body with an average width of approx. 30 metres making it amenable to bulk tonnage open pit mining.

The Bongou deposit remains open at depth and to the southwest.

The current resource estimate for Bongou demonstrates a grade, tonnage profile amenable to a potentially high margin gold project although additional scale is required.

As such PDI is now focused on identifying further mineralised granite bodies within close proximity to Bongou and within the Samira Hill Greenstone Belt.

Great start, now we look for more of the same

We see PDI’s maiden resource at Bongou as a good start for the Bonsiega project.

The project has potential for multiple ‘Bongou-type’ discoveries.
 
Drilling in the next field season will be directed at high grade targets within 20 kilometres of Bongou.
 
If PDI can make further ‘Bongou-type’ discoveries it could move the Bonsiega project towards a potential development scenario.

We look forward to PDI following up a number of granite-hosted gold prospects at Bonsiega that have shown potential for further discoveries.

The Bongou maiden resource compares well to PDI’s West African focused peers.

The high grade at Bongou sees PDI well positioned with one of the higher grade deposits of the entire ASX-listed West African gold sector, albeit at lower tonnes.

Further discoveries of a similar type would add the tonnes necessary for PDI to break away from its peers.
 
With an EV of approx. $3.7 million PDI is highly leveraged to the potential for further discoveries of high grade ‘Bongou-type’ deposits.

Disclaimer: The above is intended as a guide only. The Roadhouse accepts no responsibility for investments made from this advice, successful or otherwise.

The views, opinions or recommendations of this article do not in any way reflect the views, opinions, recommendations, of The Resources Roadhouse.

The Roadhouse makes no representation or warranty with respect to the accuracy, completeness or currency of the content. The content is for educational purposes only and does not constitute financial advice. Independent advice should be obtained from an Australian financial services licensee before making investment decisions.

Rox readies to fire at Musket and Cannonball

THE INSIDE STORY: A good deal of recent commodity market commentary has held a particular fondness for the future prospects, both short and long-term, in relation to the prices of nickel and zinc.

There are, at present, a healthy number of nickel/zinc exploration plays hitting the radar screens of these well-informed analysts and among these is ASX-listed junior Rox Resources (ASX: RXL).

The company believes it is well placed to take advantage of any price increases in both these commodities, especially nickel.

Rox Resources recently announced a maiden Mineral Resource estimate for the Musket nickel sulphide deposit, which has substantially increased the company’s Fisher East nickel sulphide project mineral resource inventory by over 100 per cent.

The Musket mineral resource estimate comprises 2.1 million tonnes at 1.8 per cent nickel containing 37,500 tonnes of contained nickel.

Of particular note is 64 per cent of the Musket resource estimate is in the Indicated Mineral Resource category, using a one per cent nickel lower cut-off.

At a higher cut-off grade of 2.5 per cent nickel the Mineral Resource contains 10,100 tonnes of nickel with approximately 75 per cent Indicated.

The resource at this higher cut-off grade is 100,000 tonnes at 10.1 per cent nickel.

Total Fisher East project resources (Musket + Camelwood) now stand at 3.6 million tonnes at 2 per cent nickel containing 72,100 tonnes of contained nickel.

Indicated resources account for 52 per cent of the total resource.

 

“This maiden resource estimate for Musket is very important for us as it displays the continued prospectivity of the Fisher East nickel sulphide belt,” Rox Resources managing director Ian Mulholland told The Resources Roadhouse.

“It has taken the overall project resources to over 72,000 tonnes of contained nickel at a grade of two per cent nickel.”

An important aspect of the Musket deposit is that it contains a very-high grade core of approximately 100,000 tonnes grading 10.1 per cent nickel.

This lies close to surface and Rox has identified it to be an obvious economic driver for any planned future development.

“Having such a high percentage of the resource in the Indicated category demonstrates how good the continuity of the mineralisation is,” Mulholland said.

“We have previously said that deposits of similar style to Camelwood don’t usually occur in isolation, and we proved that by discovering Musket.”

Rox is confident in its ground position, which it considers to be very strong with the potential to discover a lot more nickel and continue to significantly grow the project resource base.

With a discovery cost so far of around 4.2 cents per pound of nickel, which is one of the lowest in the world, that confidence seems to be very well placed.

The Mt Fisher gold-nickel project is located 500 kilometres north of Kalgoorlie and covers an area of 658 square kilometres, 488sqkm of which is 100 percent-owned by Rox with the company holding an option to purchase 100 percent of the remaining 170sqkm.

Rox’s original target at Mt Fisher was gold, however its focus shifted after its discovery of nickel sulphides at the Camelwood deposit in December 2012 proved too significant to ignore.

“Our main focus in on the Fisher East nickel project, which is really all about trying to define a big enough resource to start thinking about developing a mining operation there,” Mulholland told The Roadhouse earlier this year.

“We only discovered the nickel just over 18 months ago, and the first thing we did was complete the drilling that allowed us to define the mineral resource of about 35,000 tonnes of contained nickel.

“Our focus now is on increasing the amount of contained nickel at the project.

“The grade is there, we have already established that, but it is important now to establish 100,000 tonnes of contained nickel to enable us to develop this project into a mine with a ten year mine life producing 10,000 tonnes of nickel per year.

“That would entrench us firmly in the top five nickel sulphide producers in Australia, placing us aside companies such as BHP Billiton, Western Areas, Independence Group and Panoramic.”

Rox recently completed a program of aircore drilling at Mt Fisher, which identified three new nickel sulphide target zones.

The aircore drilling consisted 138 holes for 8,083 metres and was carried out in order to explore numerous nickel sulphide targets the company had interpreted from airborne magnetics and electro-magnetics.

“We believe these three new high-priority targets hold great potential to deliver further nickel sulphide mineralisation,” Mulholland said.

The first of the new targets is known as Cutlass and is located is along strike four to six kilometres to the south of the Camelwood and Musket deposits.

 

The other two – known as Jim’s and Fisher South – are located further west on what Rox thinks could be a possibly dislocated portion of the Mt Fisher ultramafic belt.

Results from Cutlass included:

FEAC235:
6m at 0.18 per cent nickel, 181ppm copper, 20 ppb platinum and palladium from 56m;

FEAC240:
12m at 0.30 per cent nickel, 147ppm copper, 20 ppb platinum and palladium from 32m, including 1m at 0.51 per cent nickel, 330ppm copper, 24ppb platinum and palladium;

FEAC262:
4m at 0.31 per cent nickel, 53ppm copper from 91m.

Further drilling was carried out at Red Mulga, which confirmed additional anomalous nickel over a strike length of 600m, with results including:

FEAC219:
17m at 0.35 per cent nickel, 67 ppm copper, 34 ppb platinum and palladium from 24m;

FEAC241:
32m at 0.26 per cent nickel, 36 ppm copper from 24m;

FEAC202:
16m at 0.22 per cent nickel, 51 ppm copper from 16m.

Drilling at the Jim’s prospect comprised 13 holes for 804m.

Best results included:

MFAC074:
10m at 0.26 per cent nickel, 265 ppm copper, 9ppb platinum and palladium from 32m;

MFAC067:
4m at 0.20 per cent nickel, 527 ppm copper, 16 ppb platinum and palladium from 32m; and

MFAC073:
4m at 0.21 per cent nickel, 575 ppm copper, 28 ppb platinum and palladium from 32m.

Drilling at third new prospect, Fisher South entailed 26 holes for 560m, with best results including:

MFAC092:
2m at 0.20 per cent nickel, 139 ppm copper, 3 ppb platinum and palladium from 26m; and

MFAC084:
20m at 0.12 per cent nickel, 504 ppm copper, 18 ppb platinum and palladium from 22m

“Being able to identify these three new targets is very exciting,” Mulholland continued.

“The excitement stems from each anomaly possessing values similar to the aircore values we encountered to define Musket and Camelwood.”

Rox has declared its hand in regards to its intentions with Cutlass, Jim’s and Fisher South with a ground electro-magnetic survey to be undertaken to better define the targets at each prospect prior to RC drilling.

The Cutlass, Red Mulga and Fisher South prospects are located on tenements that are 100 per cent-owned by Rox while the Jim’s prospect lies on an Option to Purchase tenement.

Rox is now in the planning stages for a ground electro-magnetic survey to better define the anomalies before RC drilling.

The company anticipates both will be undertaken as soon as possible.

Rox Resources Limited (ASX: RXL)
…The Short Story

HEAD OFFICE
Level 1, 30 Richardson Street
West Perth WA 6005

Ph: +61 8 9226 0044
Fax: +61 8 9322 6254

Email: admin@roxresources.com.au
Web: www.roxresources.com.au

DIRECTORS
Jeff Gresham, Ian Mulholland, Brett Dickson

MAJOR SHAREHOLDERS
Drake Private Investments    3.8%
Rox Directors        3%

SHARES ON ISSUE
Approx. 745 million

MARKET CAPITALISATION
Approx. $39.5 million (at 11/9/14)

Senex agrees to gas asset swap with QGC

THE ROADHOUSE BOWSER: Senex Energy (ASX: SXY) has agreed a Surat Basin gas asset swap with the PL 171 and ATP 574P joint venture partners (QGC JV).

Under the terms of the Tenement Transfer Agreement, Senex will transfer its minority interest in eastern Surat Basin permits PL 171 and ATP 574P to the QGC JV and the QGC JV will transfer its 100 per cent interest in, and operatorship of, western Surat Basin permits ATP 795, ATP 767 and ATP 889 to Senex.

 

Senex and QGC JV Surat Basin gas permit locations. Source: Company announcement

 

No cash consideration is payable by any party in respect of the tenement transfers.

The QGC JV permits are adjacent to Senex’s existing western Surat Basin assets ATP 771P and ATP 593P and form the basis of the Western Surat gas project.

On completion of the transaction, Senex will hold net 2P gas reserves of 488 petajoules (PJ).

Senex considers the asset swap as a mutually beneficial proposition adding that it positions the company to be part of the solution to the looming gas shortage in domestic and export markets.

“This is a win-win transaction,” Senex managing director Ian Davies said in the company’s announcement to the Australian Securities Exchange.

“Combining the QGC JV’s western Surat Basin assets with our own western Surat Basin acreage gives Senex the scale required to build a material Surat Basin gas business on our own terms.

“The arrangement also enables QGC and its partners to focus on the eastern Surat assets to the benefit of the greater QCLNG project.

“Senex will invest up to $40 million from existing financial resources in the Western Surat gas project over the next three years, targeting commencement of pilot testing in 2015/16 and moving to an investment decision on commercial production as soon as appraisal results support it.

“This transaction is a perfect example of our growth strategy in action.

“The new project leverages the strengths and capabilities of our thriving business in the South Australian Cooper Basin while adding a material gas project to our portfolio.”

Senex said it expects the transaction to be completed by early December 2014 and is conditional on Foreign Investment Review Board, Queensland Government, and other regulatory approvals.

Email: info@senexenergy.com.au

Website: www.senexenergy.com.au

Flinders Mines increases Eagle deposit Indicated Resource

THE DRILL SERGEANT: Flinders Mines (ASX: FMS) has released an update to the Mineral Resource for the Eagle deposit within the company’s wholly-owned Pilbara iron ore project (PIOP) in the Pilbara region of Western Australia.

 

Location of the Eagle deposit within the broader Pilbara iron ore project (PIOP). Source: Company announcement

 

The updated total Mineral Resource for the Eagle deposit is 295 million tonnes (Mt) at 54.8 per cent iron based on a +50 per cent iron cut-off.

The update consists of an increase in the Indicated Mineral Resource to 291.4Mt at 54.8 per cent iron and an Inferred Mineral Resource of 3.6Mt at 53.9 per cent iron.

The Mineral Resource is comprised of:

44.2Mt of Bedded Iron Deposit (BID) at 55.6 per cent iron;

120.6Mt of Detrital Iron Deposit (DID) at 55.2 per cent iron; and

130.2Mt of Channel Iron Deposit (CID) at 54.2 per cent iron.

“The majority of the Eagle Mineral Resource is now Indicated and is defined by areas with a nominal drill spacing of 100 by 125 metres,” Flinders Mines said in its ASX announcement.

“The small proportion of Inferred Mineral Resource is located peripheral to the Indicated Mineral Resource in areas where drill spacing is nominally 100 by 500 metres.”

The previous Mineral Resource for the Eagle deposit was 293.5Mt at 54.4 per cent iron.

Flinders explained infill drilling it has undertaken this year was designed to increase the company’s confidence of the resource to at least the Indicated category rather than to increase the overall size of the resource.

“This is an important step in ensuring bankability of the mineable PIOP resource base,” Flinders said.

“This Mineral Resource update, when combined with those of the other deposits across the PIOP in coming months, will culminate in an update to the PIOP global resource and will be integrated into the Bankable Feasibility Study, currently due for completion by the end of June 2015.

“The updated Eagle Mineral Resource Estimate…further underpins the company’s confidence in progressing the development of the Pilbara iron ore project.”

Email: info@flindersmines.com

Website: www.flindersmines.com

WHL final seismic evaluation identifies Prospective Resource

THE ROADHOUSE BOWSER: WHL Energy (ASX: WHN) has reported a portfolio of some 14 prospects with total best estimate Prospective Resources of 1,044 Bcf of gas and 31.2 million barrels (MMbbls) of condensate and LPGs.

The portfolio has been mapped on the fully-processed volume of the La Bella 3D Seismic Survey, which was acquired during November/December 2013 in the VIC/P67 exploration permit (WHN: 40 per cent Operator) in the offshore Otway Basin, Victoria, in which AWE Ltd’s, subsidiary Peedamullah Petroleum also holds 60 per cent equity.

WHL said a group of four prospects (Mylius, Mylius West, Ferrier and Ferrier South) has been mapped on the Ferrier Terrace immediately west of the La Bella Field the company considers to be characterised by stacked structurally conforming amplitude anomalies.

The company said these prospects have low geological risk and Best Estimate Prospective Resources for these features total 196 Bcf sales gas and 6.2 MMbbls of condensate and LPG, in addition to the La Bella discovery, with a 2C Contingent Resource of 74 Bcf sales gas and 2.4 MMbbls of condensate and LPG.

WHL emphasised these low risk prospects – in combination with the La Bella field – could form a core gas development in VIC/P67 with successful exploration drilling.

A full interpretation of the final Pre-Stack Time Migration volume has also been carried out, which WHL said had highlighted exploration upside within the permit.

A further range of prospects have been mapped and Best Estimate Prospective Resources for these features total 665 Bcf sales gas and 19.8 MMbbls of condensate and LPG.

WHL said successful exploration drilling of key prospects could result in sufficient resource volume to support a standalone VIC/P67 project development.

“The results of the La Bella 3D seismic survey have exceeded our expectations and it is exciting for our shareholders that the broader VIC/P67 project now has the potential for a standalone gas development,”WHL Energy managing director David Rowbottam said in the company’s announcement to the Australian Securities Exchange.

“VIC/P67 lies adjacent to the existing Otway Basin gas development projects and successful exploration of the low risk amplitude supported prospects in combination with La Bella could form the basis of a VIC/P67 development through this existing infrastructure.

“Alternatively, the results seen in the final Pre-Stack Time Migration volume indicate that potential success with the higher upside but moderate risk prospects may yield sufficient resources to justify a standalone VIC/P67 gas development.

“The company continues to note the strong demand for domestic gas on the east coast of Australia and believes the conventional VIC/P67 Prospective Resources may provide a cost competitive gas supply to these markets.

“The investment in the VIC/P67 3D seismic data has enabled greater geological definition of the permit and unlocked a range of exploration prospects.

“The potential resources in VIC/P67 could play an instrumental role in providing a long-term gas supply from the Otway Basin to the east coast Australian gas markets.

“WHL Energy is now working closely with our JV partners in the drive to prioritise and mature two prospects for drilling in 2015, this being the next step in the path to commercialisation for VIC/P67.”

Email: contact@whlenergy.com

Website: www.whlenergy.com

Imugene signs research agreement with University of Vienna

THE ROADHOUSE PHARMACY: Imugene Limited (ASX: IMU) has signed an agreement to conduct preclinical immunology experiments in preparation for the 2015 clinical trials of HER-Vaxx.

The agreement has been signed with Professor Ursula Wiedermann and her research group at the Medical University of Vienna.

Imugene said the research will focus on peptides and peptide-incorporated influenza virosomes to be used in the upcoming HER-Vaxx Phase II clinical trial.

Professor Wiedermann is head of the Institute of Specific Prophylaxis and Tropical Medicine at the Medical University of Vienna and her research group within the department will carry out the work.

Professor Wiedermann is a member of the Imugene Scientific Advisory Board and was the principal investigator for the preclinical development of HER-axx.

She has led the design of the HER-Vaxx Phase II study for gastric cancer due to commence in 2015.

“We expect this high quality research and the results subsequently generated by Professor Wiedermann and her team, to support our Phase II trial design and IND application to the US FDA,” Imugene CEO Charles Walker said in the company’s announcement to the Australian Securities Exchange.

Professor Wiedermann is a Professor in Vaccinology who has been published in over 100 peer-reviewed publications and is a renowned presenter at medical innovation conferences worldwide.

As well as the preclinical development of HER-Vaxx, she performed the Phase I clinical trial in metastatic breast cancer patients with Professor Christoph Zielinski.

Website: www.imugene.com

Invion receives Phase ii Lupus trial data

THE ROADHOUSE PHARMACY: Invion Limited (ASX: IVX) has received interim data from a phase II clinical trial of INV103 (ala-Cpn10) in patients with Systemic Lupus Erythematosus (SLE).

Data from the first two cohorts has been analysed.

In the first cohort, patients received a twice-weekly intravenous (iv) dose of either 10mg INV103 (ala-Cpn10) or placebo while patients in the second cohort received a twice-weekly intravenous dose of 30mg INV103 (ala-Cpn10) or placebo.

Invion explained the data analysed included a broad range of serum biomarkers, blood chemistries, adverse drug events, anti-drug antibodies, vital signs, and signs and symptoms of lupus.

The company said safety data from the first two cohorts of the study have demonstrated a safety profile supportive of testing higher doses in the ongoing phase II trial.

According to Invion data from both cohorts has demonstrated no pattern of adverse events.

In the first cohort, in which mild lupus patients received 10mg iv twice weekly, neither serum biomarkers nor stimulated cells showed any statistically significant pattern of response to
INV103 (ala-Cpn10).

In the second cohort, also in mild lupus patients, serum biomarkers showed no statistically significant cohort-wide response to treatment, due to baseline values at or near the normal range.

Based upon the safety profile generated from these results, Invion said the protocol has been advanced to dosing patients with mild lupus at 100mg iv twice-weekly, which represents a 10-fold increase over the highest dose used in previous clinical trials of ala-Cpn10.

“It is not unexpected that lupus patients with mild disease may not have a baseline abnormality in these biomarkers, and hence cannot show a response to treatment,” Invio executive-vice president R&D and chief medical officer Dr Mitchell Glass said in the company’s announcement to the Australian Securities Exchange.

“It was important for us to establish this safety profile in mild lupus patients, and now we look forward to leveraging this understanding into the final cohorts of the study – which include significantly higher doses of INV103, and also patients with more severe disease.

“While we will continue to collect valuable safety and pharmacokinetic data in mild patients, results to date have allowed us to open a dialogue with the FDA to enable us to study SLE patients with more severe disease, including the renal disorder associated with SLE.

“Patients with more severe lupus have higher levels of the biomarkers that we are examining and accordingly we would hope to see amelioration of these important biomarkers.

“We believe that the response from the final cohorts of this study will be pivotal for both regulatory strategy and possible partnering for INV103.”

Email: investor@inviongroup.com

Website: www.inviongroup.com

What the Analysts Say

WHAT THE ANALYSTS SAY: Interesting news and views from across the Resource Analyst universe.

Website: www.breakawayresearch.com

Company: KBL Mining Limited (ASX: KBL)

KBL Mining (ASX: KBL) is an Australian mineral production and development company largely focussing on the Mineral Hill Mine in western New South Wales.

They are currently operating at around 250,000 to 300,000 tonnes per annum from underground, producing both copper/gold/silver and lead/gold/silver concentrates.

Current resources and reserves give Mineral Hill a potential life of at least 10 years.

KBL is also looking at developing the Sorby Hills MVT lead/silver deposit in Western Australia.

The mineralisation is on granted Mining Leases, and the proposed first stage operation as considered in the PFS has received environmental approvals from the State Government.

Next steps will include completing a BFS, followed by funding and then development of what could ultimately be a long term operation.

Following successful cost cutting measures, KBL is now concentrating on a clear strategy to boost revenue at Mineral Hill.

These include the recently added lead circuit (first lead revenue was in the last quarter, with lead previously reporting to tails), the addition of a CIL precious metals circuit, mining of the high grade Pearse gold/silver deposit and accelerating underground development to open several mining areas in the Southern Ore Zone and enhance production flexibility.

The plant upgrades should allow extra value to be extracted from existing resources, and along with recent exploration success we believe there is now potential for at least a 10 year mine life.

At Sorby Hills, KBL has an advanced project with considerable scope for expansion. The current PFS is based on only 26% of resources, and there is the potential to develop this into a long life operation.

Website: www.psl.com.au

Company: Apollo Minerals Limited (ASX: AON)

Apollo Minerals (ASX: AON) will shortly embark on a high impact drill campaign targeting Iron Oxide Copper Gold (IOCG) deposits in the Gawler Craton in South Australia.
The company plans to drill several deeper diamond holes within the Mars Aurora Tank and Eagle Hawk JV’s to test for IOCG mineralisation.

Titan IOCG Project: A Potential Company Maker:

The Titan IOCG project, which consists of three JV’s, has the potential to be a company maker for AON.

It has all of the characteristics to potentially host an IOCG system.

It has 1) anomalous soil geochemistry up to 460ppm copper, 2) Iron rich haematite breccia 3) Nearby volcanic units and Hiltaba equivalent granites 4) Highly conductive zones with structural control 5) Gravity and magnetic responses similar in scale and magnitude to other world class IOCG deposits such as Prominent Hill located 110km to the east.

High Impact Drill Program; Significant Potential Upside:

AON are about to commence Phase 1 drilling to test several IOCG targets.

At the Mars Aurora Tank JV (AON earning 75%), AON will test a strong chargeability anomaly possibly associated with highly anomalous surface geochemistry.

At the Eagle Hawk JV (AON earning 75%), AON plans to test the large gravity anomaly at Bundi South and several other targets which are being identified through its recent gravity survey.

The cost of the Phase 1 drill program is expected to be $500,000 to $600,000, which would suggest circa 2,000 metres of drilling or eight holes based on an average depth of 250m.

AON has sufficient capital for further followup drilling.

HPX Strategic Alliance:

We see the attraction of Robert Friedland’s High Power Exploration Inc (HPX) to the Commonwealth Hill JV (earning up to 80%) as validation of concept that there is good potential to find a massive IOCG deposit(s) within the tenure.

We understand HPX chose to do a deal on the Commonwealth Hill project after the reviewing more than 1,500 projects worldwide.

HPX has used its proprietary EM/IP technology known as ‘Typhoon™’ to evaluate the JV tenements with several targets identified.

Four drill holes have been completed to test the geology of the region. Assay results are pending. Further exploration will be determined by HPX.

Strong Commercial Team:

The AON team is headed up by Dominic Tisdell (CEO) who is a mining engineer with significant experience, including time with Rio Tinto.

Richard Shemesian (executive chairman), a former investment banker, has significant experience in the resources sector with direct involvement in several company making projects.

Chris Anderson (technical advisor) is a geophysicist with over 35 years’ experience in Australia and abroad and was a key player in the Carrapatenna iron-oxide, copper, gold, uranium deposit discovery.

The AON team is complimented by HPX’s technical team including ex-Rio, head of exploration, Eric Finlayson (non-executive director) and Barry De Wet ex-BHP chief geophysicist.

Catalysts:

Late August: Phase 1 drilling commences at Mars Aurora Tank and Eagle Hawk JV.
September: Commonwealth Hill JV assay results.
September: Drill Results from Phase 1 Drill program.


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The Roadhouse makes no representation or warranty with respect to the accuracy, completeness or currency of the content. The content is for educational purposes only and does not constitute financial advice. Independent advice should be obtained from an Australian financial services licensee before making investment decisions.